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Stillingstittel: PhD student

Stillingsbeskrivelse:

Do you want to be a PhD student in a world-leading research environment at Oslo University Hospital Rikshospitalet?

The Norwegian PSC Research Center (NoPSC) at the Oslo University Hospital (OUH) and the University of Oslo (UiO) is dedicated to research on the chronic autoimmune liver disease primary sclerosing cholangitis (PSC). Several features make PSC an intriguing model disease; more than 80% of the patients have inflammatory bowel disease, for which the link with the biliary inflammation is poorly known. Furthermore, as much as 15-20% of the patients develop cancer of the bile ducts. A large proportion of the patients eventually need a liver transplantation, but unfortunately the disease recurs in a significant number of patients. The center comprises three research groups covering all aspects of research related to primary sclerosing cholangitis, from basic genomic and experimental studies to clinical research and clinical trials. The research environment is world-leading for PSC and counts 10-15 engaged researchers from several countries and specialties.

We have now a vacant position as a PhD fellow (3 years) in autoimmune liver diseases, funded by Helse Sør-Øst.

Duties and responsibilities

We are seeking a motivated and ambitious co-worker to take on an intriguing project; "Recurrent disease in the liver transplant: Establishing a human model of autoimmunity.- Autoimmune diseases represent a major societal challenge and proper animal models which would enable mechanistic studies are often lacking. In a recently initiated project funded by a prestigious ERC grant we are investigating the gut microbial contribution to recurrent PSC after liver transplantation and how this can be treated. In relation to this, the present PhD project comprise a series of substudies focusing on the biology of recurrent PSC, which will open many new opportunities in both clinical and basic research. The successful candidate will be part of the Genomics and metagenomics of inflammatory diseases group, led by Johannes R. Hov, who will also be the main supervisor for the candidate. The group has extensive experience with large-scale data analyses of the genetics of the host and the gut microbiota, as well as circulating biomarkers. Increasingly, the aim is to produce clinically relevant results. The group is closely related to the clinical departments, it has strong collaborations locally at the translational Research Institute of Internal Medicine, where the group and labs are located, but also regionally, nationally and internationally.

Qualifications

• Applicants must be M.D. or hold a relevant master degree within life sciences
• Experience with previous research or project work is an advantage but not a prerequisite

Personal qualities

• High working capacity and productivity
• Strong motivation
• Excellent writing and oral communication in English

Personal suitability for the position will be emphasized and taken into account

We can offer

• International, friendly and inspiring environment
• The position represents a unique opportunity for a hard-working candidate
• Startup autumn 2019

Kontaktinformasjon

Johannes Hov, Researcher, 91687143, j.e.r.hov (at) medisin.uio.no

Arbeidssted

Sognsvannsveien 20
0372 Oslo

Søk på stillingen:Klikk her

Nøkkelinformasjon:

Arbeidsgiver:Oslo universitetssykehus HF

Referansenr.:4084633543
Stillingsprosent: 100%
Søknadsfrist: 10/06/2019

PAM

numberOfPosts: 1

jobCategoriesCodes_0: http://data.europa.eu/esco/isco/C2310

abstractJV_contact_0: See jobabstractJV_description

contractTypeCodes_0: fulltime

Arbeidsgiver Navn: OSLO UNIVERSITETSSYKEHUS HF-Nevrologisk avd.RH

source: NAV