id: MDMzMTE5MDUwMDAyMTggMjYx

reference: 03311905000218

documentId: 03311905000218

connectionPointId: 261

Stillingstittel: PhD stipendiat

Stillingsbeskrivelse:

A 3-year PhD position is available at the Pediatric Research Institute (PFI) for a highly motivated PhD student on a project funded by the Childhood Cancer Society (Barnekreftforeningen https://www.barnekreftforeningen.no/).

The PFI was established as a joint university and hospital institute at the Rikshospitalet in 1959. PFI is committed to promote pediatric research through advanced science in combination with clinical practice. The aim is to obtain scientific knowledge for a better understanding, treatment, and prevention of pediatric diseases. At present five different research groups are working at the Institute and the research is mainly related to perinatal medicine, hypoxia and reoxygenation, cancer, hepatology, metabolism, and immunology. The institute collaborates extensively with a number of national and international research groups.

The project aims to improve the life expectancy of children with pediatric cancer, as childhood malignancies are still the dominant cause of death by disease among children over one year of age in high income countries. Neuroblastoma (NB) is a cancer of the early childhood, characterized by extreme clinical, biological, and genetic diversity. High-risk NB patients with primary resistant or relapsing disease are treated with one of the most intensive therapy regiments in modern pediatric oncology; nevertheless, a successful treatment is currently missing and the prognosis is poor. The main objective is to identify the critical genomic, transcriptomic, and proteomic processes of NB tumor heterogeneity, aggressiveness and clonal evolution of Neuroblastoma (NB). The successful candidate will apply different molecular biology techniques and single cell methods in combination with sequencing technologies supported by advanced bioinformatic tools.

The scholarship is based on cooperation between Dr. Lars O. Baumbusch (PFI, OUS Rikshospitalet) and Prof. Dr. Klaus Beiske (OUS Radiumhospitalet). The project will be linked to other research environments within Oslo University Hospital, national- and international research groups. The applicant will be part of a research team of engineers, fellow candidates, and researchers.

Only applicants who apply electronically via Webcruiter will be considered. There, you will find the possibility to provide a cover letter (including a short abstractJV_description of your motivation for the position), your CV (summarizing education and practical work experience and a list of your academic work and other relevant contributions) and the names and contact details of 2 referees. Foreign applicants should be prepared to provide an explanation of their degree including their University-s grading system. Please note that all documents should be in English or a Scandinavian language.

Arbeidsoppgaver

• The candidate will investigate the genomic and transcriptomic profiles of high-risk neuroblastoma utilizing modern sequencing technology and molecular biology methods
• Different molecular biology techniques will be applied, including single cell amplification, genetic, cellular, and genome-wide approaches; further comparative analysis of high resolution data
• The PhD Candidate shall participate in the faculty-s organized research training, and the PhD project shall be completed during the period of employment. The candidate must be qualified for admission to the PhD program at the Faculty of Medicine, University of Oslo: http://www.med.uio.no/english/research/doctoraldegree/phd/application/

Kvalifikasjoner

• We are looking for a highly motivated and skilled candidate with experimental background in molecular biology, biotechnology, or cancer research and with some experience or great interest in applied bioinformatics
• Applicants must hold an MSc or equivalent degree in molecular biology, cell biology, biotechnology, or related areas
• Applicants with a medical degree and with research experience (research school of 5th year project in a relevant field), as well as master students in the final stages are also encouraged to apply
• Some experience in scientific writing
• Good written and oral communication skills in Norwegian and English
• Working experience in the field of cancer research childhood diseases, sequencing data, or bioinformatics is an advantage
• Høyskole / Universitet. Hovedfag / Mastergrad in: molecular biology, biotechnology, medicine or pharmacy

Personlige egenskaper

• Strong motivation and high working capacity
• Dedicated interest in medical-biological problems
• Ability to design, plan, perform, and analyze experiments in an innovative way
• The candidate is expected to work together with engineers and other scientists in a team
• We wish to welcome a candidate with the ability to work independently, but with good communication skills
• Satisfying proficiency in the English language is a prerequisite

Vi tilbyr

• Interesting scientific topic
• Encouraged supervision and cooperation
• A challenging and friendly working environment
• 100% position for three years granted by the Barnekreftforeningen
• A favorable pension arrangement and attractive welfare arrangements
• In accordance with the OUS-s equal opportunities policy, we invite applications from all interested individuals regardless of gender or ethnicity

Kontaktinformasjon

Lars Oliver Baumbusch, Forsker, 23073372, Lars.O.Baumbusch (at) rr-research.no
Klaus Beiske, Professor, 22782423 , kbeiske (at) ous-hf.no

Arbeidssted

Sognsvannsveien 20
0372 Oslo

Søk på stillingen:Klikk her

Nøkkelinformasjon:

Arbeidsgiver:Oslo universitetssykehus HF

Referansenr.:4081770591
Stillingsprosent: 100%
Startdato: 02.09.2019
Sluttdato: 01.09.2022
Søknadsfrist: 11.06.2019

PAM

numberOfPosts: 1

jobCategoriesCodes_0: http://data.europa.eu/esco/isco/C2310

abstractJV_contact_0: See jobabstractJV_description

contractTypeCodes_0: fulltime

Arbeidsgiver Navn: Oslo universitetssykehus HF Rikshospitalet

source: NAV