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Stillingstittel: PhD research fellow

Stillingsbeskrivelse:

Org. nr: - Stillingsident: 4118177233 Presentasjon av stillingen:

PhD candidate - Role of epigenetics in diabetes development during pregnancy

Applications are invited for a 3-year position as a PhD research fellow in the EPIPREG research group, Department of Endocrinology, Morbid Obesity and Preventive Medicine, Oslo University Hospital.
The position is funded by the South-Eastern Norway Regional Health AuthorityThe candidate will work in the EPIPREG Research group to explore how epigenome-wide DNA methylation in maternal white blood cells is related to glucose regulation and risk factors for type 2 diabetes like gestational diabetes, physical inactivity, overweight and diet. Our group aims to increase the understanding about the underlying mechanisms of how lifestyle and genetics interact through epigenetics and are associated with development of diabetes, to ultimately improve diabetes prevention and treatment of the disease. The candidate will also be a part of professor Kåre I.Birkeland-s research group Type 2 diabetes and metabolism, and of Oslo Diabetes Research Centre and work with national and international collaborators.
This PhD position offers an opportunity to attain high-quality research competence, work with leading experts in the field, as well as participation at conferences and a visit to our collaborators (e.g. in Brisbane, Australia or Malmö, Sverige) to learn new methods. The candidate is expected to attain high skills in advanced statistical methods and finalize a PhD dissertation within the period. The project is led by researcher PhD Christine Sommer.

Arbeidsoppgaver

The PhD candidate will join a research team studying how different phenotypic traits are associated with DNA methylation in a pregnancy cohort. The purpose of the position is research training leading to the successful completion of a PhD degree. The EPIPREG project consists of both a biostatistical arm and a mechanistic arm. The current position will mainly work with the biostatistical arm of the project, with epigenome-wide association studies (EWAS) and meta-analysis of results from several cohorts.
Main working methods:

Epigenome-wide association studies of different phenotypes

Identify potential cohorts with similar data and invite them to participate in the meta-analysis

Meta-analysis of summary data from multiple cohorts

Follow the PhD program at the University of Oslo

Writing papers and dissertation

Kvalifikasjoner

• Master degree, or equivalent, within a relevant area such as biostatistics, molecular biology, medicine or nutrition
• The candidate must be admissible to the PhD programme: The average grade given at bachelor's level should be no less than grade C, Subjects at master's level should have an average grade of no less than grade B, Master Thesis should have grade B or better
• Good written and verbal communication skills in English are necessary (International applicants must document their English language skills)
• High statistical competence, or motivation to learn (experience in R is preferred)
• Previous experience with Unix command, GWAS or EWAS and experience with the use of computer clusters (such as Abel and Colossus at the University of Oslo) would be an advantage, but necessary training and supervision will be offered

Personlige egenskaper

• Curious
• High motivation and enthusiasm for research
• Creative thinking and analytic abilities
• Ability to work in a systematic and efficient way
• High skills in working both independently and in a team

Vi tilbyr

• Salary according to the guidelines from the Oslo University Hospital
• A welcoming and professionally stimulating international research environment
• Opportunities for national and international collaboration
• 3 months stay abroad at our collaborator-s facilities
• The possibility to attend international conferences, courses and workshops
• Attractive welfare benefits and a generous pension agreement, in addition to Oslo-s family-friendly environment with its rich opportunities for culture and outdoor activities

How to apply

• Motivation letter (with professional background, motivation, research interests and how your qualifications make you suitable for the position)
• Letter of recommendation (relevant to research)
• CV
• List of publications (if applicable)
• Applicants may be called in for an interview. Applicant-s academic and personal prerequisites to carry out the project within the EPIPREG group will be given emphasis in the evaluation process.

Kontaktinformasjon

Christine Sommer, Project leader, +47 90930391
Elisabeth Qvigstad, Administative leader, +47 98056128

Arbeidssted

Trondheimveien 235
0586 Oslo

Søk på stillingen:Klikk her

Nøkkelinformasjon:

Arbeidsgiver:Oslo universitetssykehus HF

Referansenr.:4118177233
Stillingsprosent: 100%
Startdato: 15.01.2020
Søknadsfrist: 15.09.2019

PAM

numberOfPosts: 1

jobCategoriesCodes_0: http://data.europa.eu/esco/isco/C2310

abstractJV_contact_0: See jobabstractJV_description

contractTypeCodes_0: fulltime

Arbeidsgiver Navn: Oslo universitetssykehus HF

source: NAV