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Stillingstittel: PhD Candidate position in biostatistics

Stillingsbeskrivelse:

PhD Candidate position available at the Department of Forensic Sciences, Oslo University Hospital

There is a fully funded position available for a PhD Candidate in the Forensic Biology Research Group for an individual with a strong background/ degree in statistics/ bioinformatics. The position is open from 01.09.2019, and will last until 01.09.2021. The candidate will carry out analysis of data generated using massively parallel sequencing (MPS). The work will be performed on two different platforms 1) Illumina MiSeq and 2) ThermoFisher Ion S5 System. The successful applicant will join a team with a strong focus on interpretation of evidence.

Areas of research

There are two main areas of research interest which the successful applicant will participate:

Population genetics of short tandem repeats (STRs) analysed using MPS. Norwegian populations will be analysed where the aim is to submit data to the STRidER database (https://strider.online/). An analysis of the benefits to casework using MPS compared to conventional DNA profiling - including the development of mixture modules that will integrate with our open source software `Euroformix- (http://www.euroformix.com/).
a. Comparative studies with `conventional- methods.
b. Development of nomenclature.
c. Characterisation of MPS stutters and degradation characteristics.
d. Extend Euroformix in order to take account of the specific characteristics of MPS STR systems.

Body fluid prediction using mRNA and microbial patterns for forensic applications, complementing our previous work in this area (https://doi.org/10.1016/j.fsigen.2017.05.009). Here we are interested in expanding our capability to identify body fluids/cell types, using methods like Principle Component Analysis.
a. Expand the capability to different body fluids and tissues.
b. Discover new candidate markers.
c. Study the effect of degradation on mRNA and microbiota.
d. Investigate improved efficiency gains if data from different techniques are combined together - specifically mRNA and microbiota from body fluids using existing multiplex systems.

Qualifications

• The candidate must fulfil the requirements for a PhD position at the University of Oslo.
• The candidate must be able to work as part of a team.
• Good communication skills in written and spoken English.
• Good computer programming skills (R and C are preferred).

Personal qualities

• Ability to work in a systematic and structured way.
• High motivation and enthusiasm for working with research Projects.

We offer

• A welcoming and professionally stimulating international research environment attached to a casework Laboratory.
• Opportunities for national and international collaboration.
• Salary according to current agreements.

Contacts

Ane Elida Fonneløp, Forsker, rmanfo (at) ous-hf.no

Location

Sognsvannsveien 20
0372 Oslo

Apply for position:Click here

Key information:

Employer:Oslo universitetssykehus HF

Reference number:4051584382
Percentage of full-time: 100%
Start date: 01/09/2019
End date: 01/09/2021
Application deadline: 05/05/2019

PAM

numberOfPosts: 1

jobCategoriesCodes_0: http://data.europa.eu/esco/isco/C2310

abstractJV_contact_0: See jobabstractJV_description

contractTypeCodes_0: fulltime

Arbeidsgiver Navn: OSLO UNIVERSITETSSYKEHUS HF-Nevrologisk avd.RH

source: NAV