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Stillingstittel:
PhD Candidate Organic Synthesis/Synthetic Medical Chemistry

Stillingsbeskrivelse:

Jobbnorge ID: 169592

The position

Department of Chemistryare looking for an enthusiastic and highly motivated candidate for a PhD fellowship available at The University of Tromsø - The Arctic University of Norway, Faculty of Science and Technology. The candidate will work on a project targeting the development of bioacitive compounds with relevance to antibiotic resistance. The appointment is for a period of four years As a PhD student, you will enter an international and collegial environment, and be enrolled in the Department of Chemistry PhD-school which offers developmental courses on transferable skills, conferences, social gatherings and other activities.

Department of Chemistry

Department of Chemistry is host for the Hyleraas Centre for Quantum Molecular Sciences, a national centre for excellence, the Norwegian Structural Biology Centre(NorStruct), and is partner in Centre for Bioinformatics. The Department is also host for the national graduate school in biocatalysis, BioCat

The position's field of research

The research will target the development of bioactive compounds with relevance in antibiotic resistance research. The project focuses on the design of inhibitors directed against carbapenemases using a structure-guided fragment-based approach. The work will include the design, evolution and evaluation of hit fragments targeting carbapenemases. Development of the fragments will be guided by molecular docking, NMR and X-ray crystallography. A research visit to international collaborators is expected.

The candidate will be part of the Bayer research group (https://site.uit.no/bayerlab/) and the Laczyme project (https://uit.no/prosjekter/prosjekt?p_document_id=467132) at the Department of Chemistry and will take part in their international research collaborations. The Department of Chemistry (http://uit.no/kjemi) currently has a strategic focus on drug design and discovery with special focus on antibiotic resistance research, with research groups in the fields of organic synthesis and medicinal chemistry, structural chemistry and computer modeling. Synthesis of bioactive compounds with medicinal applications plays a central role. More information about the Department of chemistry-s research activities can be found at:

http://en.uit.no/ansatte/organisasjon/forskning?p_dimension_id=88139&p_menu=28713

Contacts

For further information about the position and project, contact:

Assoc. Prof. Annette Bayer

phone: +47 776 44069

email: annette.bayer (at) uit.no

Prof. Hanna-Kirsti S. Leiros

phone: +47 776 45706

email: hanna-kirsti.leiros (at) uit.no

Qualifications

The position requires a Master degree in synthetic organic or synthetic medicinal chemistry for appointment. A solid background in organic synthesis is mandatory. Experience in molecular docking/modeling, NMR, SPR, X-ray crystallography or molecular biology are seen beneficial. Knowledge of pharmaceutical sciences will also be considered positive. The applicant must document a high level of knowledge through an enclosed Master thesis or other relevant works. The candidate will work in teams with biologists, structural- and medicinal chemists and have to demonstrate an open and positive attitude towards interdisciplinary team-work in research. Personal suitability will also be emphasized.

The applicant must be able to document proficiency in English that satisfies the Norwegian Higher Education Entrance Qualification, either as a native language, via undergraduate education in a Nordic country, or by test scores as described below. Further details about requirements for admission to PhD studies is available via links here: https://uit.no/nt/phd. Proficiency in a Scandinavian language will be considered an advantage for the position.

Qualification with a Master's degree is required before commencement in the position. If you are near completion of your Master's degree, you may still apply and submit a draft version of the thesis. You must document completion of your degree before commencement in the position.

You have to be qualified for and participate in our PhD program. If you already hold a PhD or equivalent degree, you will not be eligible for this position.

Assessment

The assessment will emphasize academic performance, motivation and personal suitability for the position. You must be willing to engage in the ongoing development of your discipline and the university as a whole. During the assessment process, emphasis will be put on your potential for research, as shown by the Master's thesis and other academic works, relevant research experience and academic performance and teaching experience and/or qualifications. Teaching experience and/or qualifications will be considered an advantage. In addition, we may consider work experience or other activities of significance for the PhD studies.

Application

Your application must include:

• CV (Maximum 2 pages) and application letter (Maximum 1 page)
• Diplomas and transcripts from your Bachelor's and Master's degrees or equivalent; the Master-s degree must be at least submitted to qualify for applying to this position.
• Diploma Supplement for completed degrees from EU universities (and applicants from non-EU universities are advised to attach an explanation of the grading system)
• Documentation of English language proficiency for PhD-studies, with a minimum score of 6.5 on each part of the IELTS test, or minimum scores of 22, 22, 22 and 25 (reading, listening, speaking and writing, respectively) on the TOEFL test.
• Copy (or links) to Master's thesis (or equivalent)
• A abstractJV_description of research performed and/or any other works (published or unpublished) which you wish to be considered. In cases of multiple authorship, your specific contributions must be described. (Maximum 1 page)
• 2-3 references and/or letters of recommendation, including contact details

Documentation has to be in English or a Scandinavian language. We only accept applications through Jobbnorge.

We offer

• Involvement in an interesting research project
• A good academic environment with dedicated colleagues
• A large degree of independence in work
• Flexible working hours and a state collective pay agreement
• Pension scheme through the state pension fund

The appointment is for a period of 4 years, and the nominal length of the PhD program is three years. The fourth year is distributed as 25 % of each year, and will consist of teaching or other duties for the department.

Remuneration of PhD positions are in salary code 1017. In addition to taxes, a further 2% is deducted for the Norwegian Public Service Pension Fund.

More practical information for working and living in Norway can be found here: Welcome to UiT!?

Generell informasjon

We make the appointment in accordance with the regulations in force concerning State Employees and Civil Servants, and guidelines at UiT. At our website, you will find more information for applicants.

UiT The Arctic University of Norway has HR policy objectives that emphasize diversity, and encourages all qualified applicants to apply regardless of their age, gender, functional ability and national or ethnic background. The university will emphasize making the necessary adaptations to the working conditions for employees with reduced functional ability.

We process personal data given in an application or CV in accordance with the Personal Data Act. You may request to not be registered on the public list of applicants, but the University may decide that your name will be made public. You will receive advance notification in the event of such publication.

Se annonsen og søk på stillingen www.jobbnorge.no

PAM

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Arbeidsgiver Navn: UiT Norges arktiske universitet

source: NAV