Stillingstittel: Two Postdoc positions in Microbial Biotechnology

Stillingsbeskrivelse:

NTNU - knowledge for a better world

The Norwegian University of Science and Technology (NTNU) creates knowledge for a better world and solutions that can change everyday life.

Faculty of Natural Sciences and TechnologyDepartment of Biotechnology

Jobbnorge ID: 124373

Two Postdoc positions in Microbial Biotechnology

Two Postdoc positions are available at the Department of Biotechnology. The positions are financed by the Research Council of Norway by the Biotek2021 research program. One project is associated the Digital Life initiative, and the other position is associated an Era-net project with partners from five European countries.

 

Information about the department

The current research fields at the Department includes Microbial Biotechnology, Analysis and Control of Microbial Systems, Food Chemistry, and Biopolymers and Biomaterials

Further information is available at http://www.ntnu.edu/biotech/research

 

Job description

The aim of the Era-net project "Z-Fuels: A novel bacterial system with integrated micro-bubble distillation for the production of acetaldehyde" is to develop an integrated process in which low value waste (e.g. crude glycerol) is converted to a valuable biofuel and/or precursor chemical (acetaldehyde) using the bacterium Zymomonas mobilis. The work tasks of the NTNU partner will be controlled micro-aerobic cultivation and analysis of metabolism in the constructed bacterial strains. Core techniques will be bioreactor cultivations, mass spectrometry based metabolite profiling, 13C label experimentation, analysis of respiration and respiratory chain analysis. The post doc will have to spend significant time in the laboratory of project partner Professor Robert Poole, University of Sheffield, UK. This is a three year position.

 

The aim of the Digital Life project "INBioPharm - Integrated Novel Natural Product Discovery and Production Platform" is to provide a new, integrated platform for the more efficient discovery and production of novel bioactive compounds with high medical application potential from natural microbial biodiversity, promoting accelerated innovation in the biopharmaceutical market. Project management is at SINTEF Materials and Chemistry. Central work tasks of the NTNU post doc will be to join the efforts of optimizing Streptomyces superhost strains for an improved success rate in heterologous production of novel bioactive compounds using Systems and Synthetic Biology approaches. Focus will be on primary metabolism through transition to secondary metabolism using 'omics technologies (gene expression, protein and metabolite profiling, intracellular flux determination) and core techniques include bioreactor cultivations, mass spectrometric protein and metabolite profiling and other molecular and physiological assays. This is three year position with a possible one year extension.

 

Qualifications

These qualifications are valid for both positions. The applicant must hold a PhD in microbial biotechnology or similar fields, and experience with experimental work is required, preferably microbial physiology and molecular biology. Experience with using mass spectrometry instrumentation and cultivation of microorganisms in bioreactors are considered as strong advantages, but candidates that are theoretically strong and have worked at the intersection of experimental 13C-flux analyses and metabolic network modelling can also be considered. However, they must be willing to spend most of the time in the cultivation and analytical labs. The candidates must document ability to work independently and in groups, and ability to publish scientific papers. Experience with supervision of students is considered an advant

Minstelønn: 0

Maksimal lønn: 0

Arbeidsgiver Navn: NTNU - Norges teknisk-naturvitenskapelig

Arbeidsgiver adresse: 7491 TRONDHEIM

Job kort beskrivelse: University and higher education teachers

Land: Norge

Region: Sør-Trøndelag

Kilde til jobbtilbud: NAV, Offentlige arbeidsformidlinger, Norge

Lønn valuta: NOK

Lønn periode: Pr. år